STEM CELLS: The TRUTH And MYTHS of 21 CENTURIES.

Instead of "gene therapy" about which it was much spoken the last century, but after a series of failures about it have already overlooked, now has ostensibly come new era - stem cells . Some compare researches in this area as opening of nuclear synthesis, others give to this opening, ostensibly begun since 1998, as new jerk to longevity and many other slogans.

On researches in this area go billions dollars in many countries of the world. New laboratories and even institutes are created which is amplified try to create a beat. Business concerns, yet not having received though any scientific results in this area, offer all interested person to enter these stem cells in body for fabulous money. Many people, not having understood in frauds of sciolists in this area, really think, that it will help them at those or other diseases. Now are inform about ostensibly already cured patients with the help of stem cells.

Has the truth about stem cells or have comments not selling scientists? It hasn't. Everywhere prospers primitiveness and impudent rudeness of sciolists.

Let's disassemble this situation from the scientific point of view. For a basis we shall take not slogans, but classical both applied biochemistry and genetics of the person.

THE TRUTH. WHAT IS STEM CELLS of the HUMAN BODY?

The stem cell is the denuclearized cell that having on the surface system reception "Self"-Unself", which can be, in view of absence of genome, is programmed under performance of this or that function in human organism. In essence it is a "clean" cell which at go in this or that body is capable to activization and to performance after its differentiation to become this or that kind of a denuclearized cell in the body, for example, leukocytes, lymphocyte, erythrocyte, cells of a skin etc. As in ripened stem cells usually there is no genetic material these cells are as though "raw cells" for performance of short-term functions in the organism. Term of life already differential cells amount from several hours to several days.

THE TRUTH. WHAT NEW KINDS of CELLS ARE REFFERED to STEM CELLS?

Since 1998, after James Tompson's applications that he has ostensibly opened embryonic stem cells, to them began to carry everything, that will get under a hand to the stupid researcher.

Thus, to stem cells now attribute two kinds of cells:

Classical stem cells;

Embryonic stem cells.

Now to embryonic stem cells attribute:

� Embryonic cells at a stage of differentiation for 5-7 day after fertilisation female egg by sperm and taking place in a female organism;

� Embryonic cells of a germ at this or that stage of the development, usually received from either miscarriages, aborted fetuses and other medical manipulations with interruption of pregnancy and removal of the germ etc.

� The Cells of a umbilical cord remaining after childbirths;

� The Cells of a placenta remaining after childbirths.

THE TRUTH. WHENCE RECEIVE EMBRYONIC STEM CELLS?

The embryonic stem cells receive, collecting living embryo from female bodies at the first stages of pregnancy which only 5-7 days developed. Allocation embryonic stem cells invariable comes to an end destruction of embryo. From one embryo it is possible to receive only 16-32 embryonic stem cells. To receive them in plenties it is necessary to have a plenty of pregnant women - donors of these cells. For these women - donors of a consequence of interruption of pregnancy can result in hormonal frustration, formation of cancer tumors in female bodies, to nervous breakdowns etc. Therefore now these embryonic stem cells are used extremely seldom and cost very dearly.

Germinal stem cells - other kind ostensibly embryonic stem cells which can be received or from medical mistakes or the interrupted pregnancy about 3 months of development of the germ. Naturally, this set of various cells as already developing the germ, instead of embryo, so adult cells from the womb surface and consequently they any attitude have no to embryonic stem cells as here are present already differential nuclear cells. Simply earlier it threw out, but now sell these waste products for fabulous money. This ostensibly stem cells can be received much in plenties and the price for them is much lower. At come of these already adult cells of other person in this or that fabric is formed the immune answer at once. Around of these cells start to be formed phagocytes and other cellular structures of innate immunity, and also complement system which are obliged to destroy alien cells for the given organism. There is an inflammatory purulent process on destruction of these alien cells. In result these alien cells for your organism or are destroyed by immune system, or regenerate in cancer cells.

Where do still ostensibly stem cells come from?

1. Umbilical cords, placentas and amniotic fluid - these adult differential cells also for some reason attitude to stem cells which can be received from various fabrics connected with course of pregnancy. These waste products of pregnancy course were thrown out earlier, but now at softhead there is an opportunity on these waste products well to earn additionally. In the Internet it is possible to meet advertising about sale cheap stem cells.

Many animals eat the self or another's placenta. It is, first of all, jackals. Our doctors that engage in introduction of stem cells, force some patients to act on jackals - to consume in inside organism another's cells of the umbilical cord and the rests of the placenta. The truth, they do it with a clever kind and for the big money.

2. Nervous cadavers cells - these cells can be received from the certain areas of the body already after death of the person more than 20 hours. These, ostensibly stem cells, also are differential with a nucleus and they have no any attitude to stem cells.

As we see, to classical stem cells now carry already differential cells, as with a nucleus, but denuclearized from which are already constructed those or other fabrics (a brain, a placenta, umbilical cords etc.). Therefore to speak about this direction as about last achievements of science in the field of medicine it is not necessary, as all this primitive fabrications of people which are not having elementary knowledge in the field of biology, biochemistry and genetics.

THE MYTH. EMBRYONIC STEM CELL ARE CAPABLE TO BE TRANSFORMED TO ANY OTHERS OUTSIDE OF A FEMALE ORGANISM

Let's consider more attentively process of mitosis egg after impregnation. From the point of view of classical biochemistry, after impregnation of female egg and its premises in the female organism, in the beginning begins process of mitosis this egg on two, then on four, then on 8, further on 16, 32 and 64 cells. Further there is a differentiation of cells from which further are formed cells of the skin, heart, a brain etc.

By stages of simple mitosis impregnation egg its volume is not increased, but there is a usual doubling of cells. It seems as if from these cells probably in further can received any cell. However it is not necessary to forget, that each cell functions not in itself, but in close community and under the control of the general genetic system. And what of these cells will form in the cell of the skin and what in the nervous cell is supervised by the general genetic system incorporated in genome of egg. Any chaos and any unguided process does not proceed, as it further can result in the most serious infringements in the future child. Furthermore the general genetic system itself distributes between these cells, in what it will be differentiated then.

Can now undertake this management this or that expert? Certainly, no. We still know about this process more very few to try to operate it. Therefore many experts who try to deal with these problems to point, that it is practically impossible to foresee, as will proceed this or that process in a whole. There are uncontrollability process of the differentiation. Also we should know, that this differentiation can proceed only under the control itself egg genome. We, at separation embryonic stem cells, destroy complete unity of it embryo and we break the general management of embryonic cells. Therefore from the biochemical point of view we can assert, that the separation embryonic stem cells from embryo and the female organism results in unguided genetic processes of the further development of these cells. The mankind has not reached while such level of understanding of genome management some genetic processes in the cell to try to take this managerial process in the self hands.

Therefore we have unfavorable results of 7-years researches at management of process differentiation embryonic stem cells.

To aspire to knowledge of differentiation process in the beginning it is necessary to learn a control system of those or other cells, both in separate body, and as a whole in all organism. We yet do not know it, and already some declare, that they from these stem cells can create this or that fabric.

The nonspecialist can declare it only. You see to create this or that tissue consisting of millions of different cells (consisting and from muscular cells, and from connecting, with a supply of arterial blood system and venous, with the built - in nervous cells both incorporated all this an overall aim and millions biochemical processes carrying out synchronously) are necessary decades.

Besides to receive these separate cells, for example one million, we should collect them from 40 000 women - donors. Cost of separation of these cells will cost for us from 200. 000, up to 400. 000 $ on one woman, and as a whole only cost of these raw cells will make about 10 000 000 000 $. In addition work with these cells experts - professionals in modern laboratory as much will cost. The total cost of the received fabric from embryonic stem cells will make about 20 - 25 billion US dollars. But guarantee synchronous work of all these millions cells in a fabric during even 5 years nobody can not.

As a result of it we have: 40 000 women - donors which have propensity to cancer diseases; nobody can not guarantee reliability of this tissue, that has astronomical cost at the received; but at introduction of this tissue to 1 patient we form at him either a cancer tumor, or rejection. As they say in a proverb - "The Mountain has given birth to the mouse".

Both with theoretical, and with practical the points of view we have full absurdity.

Therefore with full confidence it is possible to assert, that existing applications in this area are profanation.

Really, many start to understand it and if in the beginning researches in area of embryonic stem cells were given out as advanced achievements and in them were put huge investments. Now already speak about hopelessness of researches in area of embryonic stem cells and investments in these researches are sharply reduced.

THE MYTH. CLASSICAL STEM CELLS CAN BE TRANSFORMED TO ANY CELLS UNDER THE INSTRUCTION OF THE DOCTOR

Basically even of such problem definition specifies nonprofessionals of the researcher. In our organism each cell carries out the definite function both all and all is predetermined beforehand. Any chaos and confusion in our organism does not happen. At the same time if it is necessary by organism the same cell can carry out various functions. For example, a liver cells under certain conditions reprofile in connecting cells. It is formed the cirrhosis in the liver. However at restoration of the broken biochemical processes they again will be transformed to cells of the liver.

Also there are changes and to muscular cells at sportsmen. At the big training spells the organism in plenties synthesizes muscular cells. However after the training of employment muscular cells can be transformed in fatty, but after the beginning of training again can turn in muscular. It is known to each sportsman. Therefore transformation of one cells to others to human organism is carried out at direct management on the part of the body. And only the organism determines necessity of transformation of functions of this or that cell. The human organism does not react to unself instructions. If in the body will be the cell with the program that will be distinguished from associates, so it will be immediately destroyed, or it starts to function as the cancer cell. You see that cancer cells also are formed by our organism, but as against the normal cells which are taking place under the control of human organism, they develop by itself programs.

Classical stem cells can be transformed under the control of human organism, in view of feature of their structure (absence of a nucleus and accordingly genome, therefore they can not be used at cloning) to cellular structures of blood, immune system. They can be never transformed into cells of a cardiac muscle, brain cells and many other nuclear cells, as in them there is no nucleus. These elementary laws of genetics are for some reason ignored. And now are distributed applications, that postulates of development genome by Mendel too need to be thrown out in a waste-paper basket as these sciolists reject them.

Thus, we see, that the orgy with embryonic stem cells results in ignoring all laws which are turned out by mankind for centuries in the field of cellular biochemistry and genetics. They are ready to reject everything to try to protect one's own interests. It is primitiveness and nonprofessionals.

THE TRUTH. PROBLEMS ALREADY ARISING WITH USE EMBRYONIC STEM CELLS

1. They are difficulty differentiated in homogeneous target tissue.

Comments of the author: As embryonic stem cells are in process of mitosis female egg, that, at absence of their management as from the side egg (as it is destroyed), and on the side of the female organism (as they are separated from the parent body), process of their further differentiation is carried out chaotically, as against the body where they are constantly supervised by vital systems of a different level (cellular, tissue, at a level of body and at a level of all organism).

2. They are problems with immunity - embryonic stem cells from the casual donor, probably, can be rejected immune system after transplantation (effect of Yushenko).

Comments of the author: In spite of the fact that embryonic stem cells yet differentiation, however at inject in patient organism they are determined by immune system of the owner as nonself and the immune system starts them to destroy. On a place of inject embryonic stem cells there is an inflammatory process. If it is a lot of such injects, that, as see for example at the President of Ukraine Yushenko V., the volume of the inject place embryonic stem cells is increased, in the beginning this place reddens because of the arisen inflammatory process, and then appear in the plenty such as spots (products of destruction of alien cells are deduced by immune system), and then are formed pockmarks. (See photo).

3. Oncogenesis - embryonic stem cells are capable to formation of a tumor or formation of a tumor in the subsequent.

Comments of the author: If embryonic stem cells are not destroyed by immune system of the person the staying cells develop under other genetic laws, than cells of the owner. You see that embryonic cells should go other genetic way, than to cells of the organism of the owner. For example, you have injected embryonic stem cells to the person at 30-35 years age. Cells which continue to function in the organism are at a stage of development adult statuses, and embryonic - at a stage of embryo. And between them all time will be a difference in genetic development about 30-35 years + 9 months. Naturally, according to mine 8 postulates of development the genome person, between these cells will be the dysfunction that to resulting in formation of the cancer at this or that stage of genetic development of the body.

4. They is destruction of development of human life.

Comments of the author: The paradox arose - to keep to someone life, we should destroy other just arisen lives and also to harm to parent organisms. From the point of view of human morals and ethics is a blasphemy. Therefore both the Christian church, and all sane people protest against such approach to human lives.

THE TRUTH. WHAT FOR TO THE PERSON TO ENTER ANOTHER'S STEM CELLS IF THEY ARE SYNTHESIZED BY MILLIONS IN HIS ORGANISM?

Denuclearized stem cells are constantly synthesized by nuclear cells of the bone brain. Infringement of this process results in development of an anemia, and elimination of this infringement now is carried out due to change of the bone brain from the appropriate donor.

Thus, at the person, that not suffering an anemia, stem cells are synthesized by millions in the bone brain and they act for activization in a spleen and thymus where cellular structures of acquired and innate immunity are formed of them. In the thymus on nondifferentiation stem cells on the surface is attached the acquired receptor reacting to a concrete kind and strain of a pathogenic microorganism. Therefore from stem cells it is formed active lymphocyte groups T-killer, �-suppressor, �-effector, T-remember.

On the other hand on stem cells in the spleen on the surface is attached the innate receptor reacting on all nonself. In result is the given made active cell, that capable to form an antibody.

Precisely also from stem cells, alongside with lymphocytes, leukocytes and other denuclearized cellular structures are formed thrombocytes, erythrocytes.

As we see, at each person every second from stem cells tare formed he various cells responsible for those or other functions in the body. But all these processes are strictly manageable on the part of the organism which precisely operates this process. And in the body can not be such that from stem cells, for example, within one week were formed only lymphocytes, and then within the next week only thrombocytes etc. The organism itself determines how many stem cells at present will be directed in thymus that from them were generated lymphocytes such as �-killer, and how many will be directed on formation of leukocytes. Saturation of the body by one denuclearized cells further can not result in their superfluous formation. The organism will start or to reduce quantity synthesized stem cells in a bone brain or to form other denuclearized cells. Thus, process of transformation stem cells in those or others cells is carried out under the strict control and for everyone synthesized stem cell is already determined its further transformation. Anything chaos and anything processes unguided on the part of the organism.

There is a question. If all is already beforehand predetermined for each cell so that will be with cells which are subsequently injected? With again injected stem cells in those or other tissues can be carried out the following processes:

1. As transformation stem cells in differential is carried out in this or that body of the person at introduction stem cells of the given person in body where this specialization is carried out, natural process will proceed. However this operation basically is senseless.

2. At injection stem cells from nonself organism in the body of the patient there will be a destruction of this nonself cell by immune system. In this case, that the nonself cell not was is destroyed it is necessary to enter the drugs overwhelming immune system of the patient.

3. At injection stem cells of the given person in anything tissue, these innate cells in the beginning should get in that body in which they will be specialized and only then they can carry out those or other functions which it will be programmed by the organism.

4. If stem cells will not be made active in this or that body and they will not carry out those functions which to them will be transferred with an organism, they will develop under the own program and it will be accordingly the cancer cell.

As we see, basically, manipulation with stem cells of anything new to our body does not give, at the best, has overloads a control system of the organism by additional strain, in the worse - results in formation of cancer cells.

THE TRUTH. THERE ARE DIRECTIONS IN MEDICINE THAT REALLY ARE PERSPECTIVE FOR INVESTMENT

At the reader can arise the question, that those or other widely promoted researches now basically are deadlock. Scientific researches in this area in general it is necessary to stop and hope, that can be accidentally will be openly an immortality of the person.

Certainly, no. Already there are perspective researches in the field of restorative medicine. This medicine in the concept recognizes that the person should be constantly healthy, and if he has those or other infringements in the body, they should be restored up to a healthy status and, further, it is necessary to support only this healthy status.

Thus, this direction of medicine allows gradually to learn to manage those or other biochemical processes, as at a level of a cell, and separate bodies. It allows each person to understand functioning of the organism better and to study to understand it. In this case it is possible to learn each person to manage of the health and to reduce quantity of unhealthy displays and to reduce the processes resulting in fast ageing of the organism.

Why this restorative medicine does not find a recognition at physicians? Yes because this medicine sets as the purpose to do of patient - healthy. In this case the quantity of patients will be reduced sharply, including with chronic diseases. The need in therapists, surgeons, endocrinologist and other doctors will be reduced sharply. The oncological centres, the centres for patients with cardiovascular diseases etc. will be not necessary, and also private clinics and many other.

It is natural, that doctors to make a hostile demonstration against that they can remain without a profession.

Is it favourable to the patient? Naturally, it is very favourable to patients as at the best in one - two year, he becomes for ever healthy and he will not depend on whim of the doctor.

Besides it is favourable and to the state as instead of ill people (from which the problem even to choose a little thousand people for service in army) it will receive a healthy society.

Therefore it is necessary radically to change the concept of our public health services, and instead of maintenance, with the help of drugs that are blocking of symptoms, and to keep alive the unhealthy status of hundreds millions people, it is necessary to form a society of healthy people.

There is a question - What next profanation in the field of medicine it is possible to expect from primitive experts?